I connect to a remote machine. The remote machine had a center region that did not respond to mouse clicks, apparently there was an invisible window that was capturing mouse clicks.
That invisible window was in the center of the screen and every time I clicked in that region the top (focused) window was getting into background. Then i captured the handle and the app owner of that window.
Here is a screen with details of that window handle

The application is the dimdim plugin for screen sharing